28 Researchers jobs in Canada

Data Analysis Team Lead, In-line Inspection

Vancouver, British Columbia DarkVision

Posted 27 days ago

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DarkVision, a Koch Engineered Solutions company, is seeking a Data Analysis Team Lead to join our fast growing In-line (pipeline) Inspection team in North Vancouver, BC . DarkVision leverages cutting-edge proprietary acoustic imaging technology to deliver industry leading asset inspection services, capable of detecting defects as small as a few millimeters. As an ILI (In-Line Inspection) Data Team Lead, you will manage a team of Data Analysts to produce accurate inspection reports critical to the safe operation of oil and gas pipelines.

The ideal candidate has experience leading technical teams to deliver mission-critical results in a fast-paced, entrepreneurial environment. You bring a passion for operational excellence, process optimization, and challenging the status quo. Join our innovative team - comprising experts in machine vision, imaging, computer graphics, and data analytics - as we continue building the world's most advanced platform for industrial imaging and pipeline diagnostics.

Our Team

Our Data Analysts utilize 3D data visualization software and human-in-the-loop machine learning processes to meticulously analyze ultrasound datasets. The outputs of these analyses result in critical insights that enable our clients to make data-informed decisions on the operations and maintenance of multi-million-dollar infrastructure assets.

What You Will Do

  • Learn the delivery standards and workflow processes for your assigned ILI product line
  • Regularly check in with team members to assess capacity and remove roadblocks or inefficiencies
  • Through frequent 1:1 meetings, track team members' progression in their role, deliver constructive feedback, and ensure they receive proper recognition for their work while building a roadmap for their career development
  • Facilitate communication between your team and other teams and upper management
  • Ensure employees are aligned with the company vision, and that the goals and direction of the team help drive achievement of the vision
  • Facilitate the improvement of workflow procedures and best practices; seek out new solutions, seek feedback, and investigate and implement improvement opportunities
  • Review projects assigned to Analysts on your team; you are responsible for the content and delivery of projects
  • Partner with Recruiting and other Team Leads to recruit and evaluate candidates; a high volume of growth and hiring is expected
  • Make informed recommendations for hiring, raises/promotions, performance management, and further training
  • Develop new and improve existing processes and standards
  • Set project deadlines, assign project leads, and manage follow-up requests
  • Forecast team capacity vs. projected projects, offering transparency to stakeholders

Who You Are (Basic Qualifications)

  • At least 2 years of engineering or science study at university, college, or technical school
  • Experience managing a team producing client deliverables (e.g. reports, analysis)
  • Experience managing early to mid-career individuals
  • Experience leading process improvement initiatives

What Will Put You Ahead

  • Experience in the Oil & Gas industry (e.g. ILI, pipeline or piping integrity, NDE/NDT, well integrity, well logging) or industrial asset inspection services
  • Experience managing teams with at least 5 team members
  • Experience in rapidly scaling an operation or team
  • Able to disseminate complex information and generate pragmatic solutions
  • Able to assess and adjust work processes to meet scaling requirements; delegate and prioritize work effectively among the team

For this role, we anticipate paying $85,000 - $110,000 CAD per year. This role is eligible for variable pay, issued as a monetary bonus or in another form.

At Koch companies, we are entrepreneurs. This means we openly challenge the status quo, find new ways to create value and get rewarded for our individual contributions. Any compensation range provided for a role is an estimate determined by available market data. The actual amount may be higher or lower than the range provided considering each candidate's knowledge, skills, abilities, and geographic location. If you have questions, please speak to your recruiter about the flexibility and detail of our compensation philosophy.

Who We Are

As a Koch Engineered Solutions company, DarkVision provides high-resolution acoustic imaging technology that offers significant improvements over existing ultrasonic and other imaging technologies on the market today. We serve customers in a variety of industries, such as public infrastructure, energy and pipelines, power (renewables and conventional), aerospace, manufacturing, automotive and others.

At Koch, employees are empowered to do what they do best to make life better. Learn how our business philosophy helps employees unleash their potential while creating value for themselves and the company.

Additionally, everyone has individual work and personal needs. We seek to enable the best work environment that helps you and the business work together to produce superior results.

How to Apply

If you have the above qualifications, we would like to hear from you. We thank all applicants in advance, but please be advised that only those selected for an interview will be contacted.

We are an equal opportunity employer. If you require accommodation or assistance at any time during the application or selection processes, please submit a request by following the directions located in the FAQ section at the bottom of the kochcareers.com webpage.

Successful candidates will be required to complete a criminal background check.

keywords: team lead, supervisor, leadership, management, supervision, analyst, analysis, reporting, reports, pipeline integrity, in-line inspection, ILI, asset inspection, condition monitoring, anomalies, cracks, deformation, metal loss, geometry, well integrity, pipes, piping, oil & gas, upstream, midstream

#LI-JN1

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Request for Proposals: Freshwater Literature Review and Data Analysis

Toronto, Ontario Wildlife Conservation Society Canada

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Job Description: Salary: Maximum fee of $35,000 Request for Proposals Freshwater Literature Review and Data Analysis Commencing for October 2025 to March 2026 18 July 2025 PROPOSAL DEADLINE: Monday, September 8 by 5pm EDT PROPOSALS DELIVERED TO: Wildlife Conservation Society Canada 1.0 Background Wildlife Conservation Society (WCS) Canada is a national non-governmental organization with a mission is to save wildlife and wild places in Canada through science, conservation action, and by inspiring people to value nature. WCS Canada is affiliated with global WCS programs in more than 60 countries, and we are active at the science-policy interface in Canada and internationally. This RFP is issued by WCS Canadas Ontario Northern Boreal program, active since 2004 in the far north. As one of the few organizations with a continuous scientific presence in the region, we lead field-based research on large mammals, freshwater fish, and peatlands; co-develop programs with First Nations; collaborate with academic, government, and Indigenous researchers; and contribute to policy development to guide conservation decisions. 2.0 Contracting opportunity WCS Canada producing a report summarizing multiple years of freshwater ecological data that has been collected on the water quality, water chemistry, fish contaminants, and benthic invertebrates in northern boreal rivers in Ontario. We are seeking proposals (RFP) from qualified individuals or groups to support the completion of this report. We are requesting that individuals or groups submit a proposal outlining their qualifications, relevant experience, and proposed approach to conducting a literature review and statistical analyses of previously collected data. This work will inform and support the creation of a comprehensive and useful summary report by WCS Canada that outlines the status and trends in these northern boreal rivers. 3.0 Proposal Administration All requests for clarification and questions concerning this RFP must be submitted in writing no later than 5 September 2025 via email to Brianna Kim, Finance and Administrative Manager (indicate Freshwater Literature Review and Data Analysis on the subject line). Responses, if determined appropriate by WCS Canada, will be issued in writing to all known proposers. Proposals, plus attachments, are to be submitted in e-form to: Brianna Kim, Finance and Administrative Manager, WCS Canada may request an interview of any proposer (vendor). Such a request for an interview does not constitute a contract award. Proposals must be received no later than 5:00 PM, 8 September 2025 Key Dates:Last day to submit questions 7 September 2025 Proposals due8 September 2025 Interviews of proposers 11 to 18 September 2025 Notice of Award by 25 September 2025 4.0 Scope of Services and Desired Qualifications The services and deliverables to be provided by the proposer: Freshwater data analyses:Conduct an analysis of the spatial and temporal patterns of previously-collected data on fish contaminants, water quality, water chemistry, and benthic invertebrates in XXX (geography of the data analysis from watersheds over X years; andWhere applicable, compare findings to appropriate benchmarks and reference data from other relevant regions or studies; andProvide a clear interpretation of the data, supported by the freshwater literature review (below).Freshwater literature review:Conduct a focused review of both formally-published, peer-reviewed literature and grey literature (e.g., government reports, technical memos, unpublished studies) related to fish contaminants, water quality, water chemistry and benthic invertebrates from northern boreal river systems. The review should prioritize sources that directly inform or contextualize the interpretation of the collected data; andOrganize identified literature into a database that includes a summary for each resource.Provide assistance and support for summarizing the literature review and data analyses into a final report to be written by WCS Canada staff. The selected proposer is expected to have the following qualifications: Must have experience with freshwater ecological monitoring and research, including familiarity with common approaches used for: freshwater ecological monitoring, freshwater statistical analyses, and freshwater literature reviews;Additional preference will be given for experience with ecological monitoring and research in northern boreal rivers;Must be familiar with ecological analyses in R; andBe familiar with WCS Canadas mission and programmatic activities. 5.0 Length of Engagement The term of engagement is for an approximately 6-month period ending March 30, 2026. 6.0 Proposal Content Proposals should be clear and concise and should address in detail, and with appropriate documentation, each of the items listed below. WCS Canada may request clarification of any proposal during the evaluation process, but is not bound to do so, and proposers should not assume they will have any further opportunity to clarify their proposals subsequent to the proposal due date. Each proposer is requested to submit, on or before the submission deadline, a package containing its proposal addressing the following items in the order listed: A. Technical Qualifications 1. Contact Information On a single cover sheet, please provide:Contact information for the lead individual(s) who are anticipated to work on the project, including e-mail addresses, telephone number, and street address.Web address (if relevant).Year proposer was established (if relevant).Size of proposer (if relevant).List of proposed staff assigned to this project (if relevant).Signature of Principal and date of the signature. 2. Overview (1-page maximum) Proposers should provide a summary of their understanding of the services and deliverables that will be their responsibility and a description of the methods they will use to achieve those objectives, including technical quality assurance, and general management practices for comparable projects. 3. Qualifications Proposers are requested to provide detailed information that demonstrates the following:Experience providing the services requested in this RFP;Proficiency with projects of comparable size and complexity; andDemonstrable commitment to diversity and inclusion of staff and subcontractors. 4. Timetable/Schedule Proposers should produce a draft schedule that outlines critical milestones for the work. 5. Resume(s) A resume/CV of the individual(s) proposing to conduct the work should be attached, which must outline and explain the relevant experience of the individual(s) with similar previous projects. Upon award of the contract, substitutions of personnel will not be allowed without the prior written consent of WCS Canada. 6. References Proposers are requested to provide examples of up to three (3) similar projects, recently completed or in progress, with the following information for each:Description of the workName of a contact person who can provide a reference References may be contacted directly by WCS Canada. B. Fee Proposal Maximum Fee The total proposal fee shall not exceed $5,000 CAD, inclusive of all applicable sales taxes, administrative expenses, and any other project-related costs.Base fee ___Additional fees (e.g., information technology infrastructure costs, administrative support charge) ___ Total ___ 3.Other services Provide information regarding how any requested additional services will be charged (e.g., personnel with titles and hourly or per diem rates). 7.0 General Conditions of Proposal Submissions The following general conditions apply to all proposals submitted in response to any RFP issued by WCS and WCS Canada (collectively referred to below as (WCS Canada):Non-Binding: WCS Canadas solicitation of proposals in response to any RFP does not commit WCS Canada to award a contract, and this RFP is not an offer to enter into a contract for the services to be provided as described herein.Proposal Materials and Costs: WCS Canada is not liable for any costs incurred in the preparation, submission or negotiation of a response to its RFP or incurred for any other purpose or reason in connection with the RFP. No materials submitted with this RFP will be returned.Confidentiality: All information and material contained in any WCS Canada RFP or issued by WCS Canada or any of its agents as part of any WCS Canada RFP process is confidential and is the exclusive property of WCS Canada.Modifications: As a condition of award, WCS Canada may request any proposer to make revisions, additions, or deletions to its proposal.Subcontractors: After award of contract, WCS Canada will have no obligation, financial or otherwise, to any subcontractor of the awardee. Nevertheless, any subcontract will be required to be subject to and consistent with the prime contract between WCS Canada and the awardee, and WCS Canada may require any subcontract to include specific terms and conditions.Reserved Rights: WCS Canada at any time in its sole discretion may, without notice and without liability to any proposer or any other party for their expenses incurred in the preparation of the responses hereto or otherwise, do any and all of the following:Amend or withdraw this RFP;Accept or reject any and all proposals received in response to this RFP;Award the contract to a proposer other than the proposer offering the lowest fee;Request additional materials and clarification or modification of any submitted proposal;Extend the time for submission of all proposals after notification to all prospective proposers;Terminate negotiations with a selected proposer and select another proposer;Take such action as WCS Canada deems appropriate if negotiations fail to result in a signed agreement within a reasonable amount of time; and/orTerminate or modify the solicitation and selection process at any time and re-issue the solicitation to whomever WCS Canada deems appropriate. The selected vendor will be required to execute a written agreement with WCS Canada, including terms generally consistent with those set forth in Appendix A hereto, effective upon the date the written agreement is executed by both WCS Canada and the selected vendor. 8.0 Evaluation and Selection Criteria Selection Process:WCS Canada will review and evaluate all proposals to determine each proposer's rating. This evaluation may include a request to interview proposers and for proposers to virtually present their proposals for purposes of clarification.The proposal offering the most advantageous terms based on the criteria below will be selected for the award. WCS Canada may reject any and all proposals if, in its sole opinion, no proposal satisfies its criteria. Evaluation Criteria: The evaluation criteria and weight will be as follows: Demonstrated technical capability to provide the services (50%);Project-related experience (25%); andClient references (25%) APPENDIX A CONTRACT, INSURANCE, AND REGULATORY REQUIREMENTS 1. Payment Contractor will submit invoices for its work, in a form acceptable to WCS Canada, to its contact for review, who will submit the invoices for payment. Payment is subject to acceptance of the services. Contractor will be paid without deductions for income taxes or other sums which employers in Canada are required to deduct from employees wages. Even though income tax and other deductions are not made by WCS Canada, Contractor should be aware that WCS Canada may be obligated by Canadian regulations to report to Canada Revenue Agency total annual amounts paid to Contractor. Contractor will be solely responsible for the payment of all withholding and other taxes, of whatever type or nature, arising out of or related to its engagement under this Agreement and agrees to and hereby does indemnify and defend WCS Canada and its directors, officers, employees, independent contractors and agents against any claim relating to such taxes. WCS Canada will pay approved fees and expenses within thirty days after receipt of acceptable documentation. 2. Relationship of the Parties Contractors relationship to WCS Canada under this Agreement is that of an independent contractor. Nothing in this Agreement will be deemed to constitute a relationship of employer-employee, joint venture, partnership, agency, or legal representative between Contractor and WCS Canada for any purpose. Neither Contractor nor any of its employees, independent contractors or agents will receive the health insurance, sick leave, vacation, pension, retirement savings plan or other fringe benefits, or severance or termination pay, associated with regular employment at WCS Canada. 3. Termination Either party may terminate this Agreement without cause by furnishing at least 30 days written notice to the other. In such event, Contractor will be paid only for services actually rendered to the date of termination. With reasonable cause, either party may terminate this Agreement immediately upon written notice to the other. Contractor shall not incur any additional expenses between the date of notice of termination and the date of termination without the prior written consent of WCS Canada. 4. Confidentiality Contractor warrants that it will maintain in strict confidence WCS Canadas Confidential Information (as defined below) to which it has access during the term of this Agreement. Contractor will treat WCS Canadas Confidential Information with the same standard of care that it uses in maintaining its own Confidential Information, provided that that standard is not negligent. Contractor will use WCS Canadas Confidential Information only as is required by this Agreement, and will not reveal it to a third party without the prior written consent of WCS Canada, or unless it is required by law to reveal it. Confidential Information means information concerning each partys affairs, activities, research, proposals, projects, finances, property or method(s) of operation, trade secrets, know-how and similar information. Confidential Information does not include information which (a) is already known through lawful means to the receiving party before the other partys disclosure, (b) after disclosure, becomes generally known to the public through no breach or fault of the receiving party, (c) a party receives from a third party who is free to make such disclosure without breaching any legal obligation to the disclosing party under this Agreement, (d) the receiving party develops independently as evidenced by its own written records, or (e) is required to be disclosed by judicial or administrative process, in which case the party required to make that disclosure will notify the other of the obligation and cooperate reasonably with that partys effort to bar or seek a modification of the order. The term Contractor for purposes of this section shall include Contractor,

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Research Associate

Saskatoon, Saskatchewan Rack Petroleum

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Reporting to the Ultimate Yield Research & Certification Manager, the Research Associate will play an integral role as part of the Ultimate Yield (UY) research team, contributing to agronomic research initiatives with the goal of optimizing crop production. This position will be responsible for establishing, maintaining and evaluating research plots with the intent of supporting data-driven insights to advance agricultural practices.

Position Responsibilities:

  • Management of plots while maintaining strict adherence to research protocols
  • Operation and basic maintenance of research equipment, including, but not limited to tractors, sprayers, plot drill, spreaders, combines, loading and securing equipment on trailers, driving trucks and trailers
  • Planning and execution of field applications (i.e. seeding, spraying, harvesting etc.), including organization of inputs and materials needed
  • Accurate and thorough in-field data collection
  • Coordination with both research and agronomy teams to ensure all protocols are conducted at the correct time and stage (in-season field applications, data collection etc.)
  • Regular scouting and maintenance of research plots
  • Operation of technology used at research plots including drones, cameras etc.
  • Problem solve issues observed in the field
  • Assist the research team in sorting and organizing data
  • Assist the Research Manager with planning of trials and protocols
  • Contribute to team development of new trial ideas (field trials or technology to test)
  • Assist Ultimate Yield advisors in-field activities as needed (soil sampling, scouting, tissue testing etc.)
  • Other duties as required

EDUCATION AND EXPERIENCE:

  • University Diploma or Degree with a focus on Agriculture
  • Practical work experience in the agricultural sector
  • Ideal candidate has farm equipment operating experience

OTHER REQUIREMENTS

  • Exceptional time management skills and the flexibility to work longer and varied hours through peak season(s)
  • Experience in crop scouting / crop diagnostics
  • Excellent interpersonal skills and the ability to communicate effectively to all levels of staff and management
  • Self-motivated and able to work independently with minimal direction
  • Strong attention to detail with a focus on accuracy and confidentiality
  • Mechanically inclined and able to troubleshoot and repair minor mechanical issues

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Research Associate, Evaluation

Toronto, Ontario Blueprint ADE

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Company name: Blueprint
Position title: Research Associate, Evaluation
Physical location : Toronto, ON
Hybrid role – Available to work at least three days per week in office
Travel – Occasional travel within Canada
Employment status: Full-time, Regular
Hiring Range: $69,000 - $85,000
Vacancy status: Existing 

About Blueprint
Blueprint helps decision-makers use data and evidence to tackle complex public policy challenges and improve outcomes for people across Canada. As trusted advisors to government, community, and industry leaders, we work across a wide range of policy areas, including employment, income security, mental health, child and youth development, housing, community safety, and justice.

Using an interdisciplinary approach, we deliver solutions that integrate policy analysis, strategic program review, applied research, data analytics, measurement, and evaluation—ensuring policies and programs maximize public value and make life better for Canadians.

About the role 

As an Associate, you will play a central role in delivering high-impact work for our public sector and nonprofit clients. You will work as part of an inter-disciplinary team on projects that span evaluation, measurement, performance improvement, strategy, policy design, strategic program review, and service transformation. You’ll engage directly with clients, support evaluations, develop evidence-based insights, and contribute to practical solutions that inform decision-making and drive better outcomes.

You bring curiosity, strong analytical and reasoning skills and a familiarity with research methods. You are adaptable, organized, and able to manage multiple priorities while meeting deadlines efficiently. The ideal candidate thrives in a fast-paced environment, that blends rigorous evaluation and analysis with a collaborative, client-oriented approach. This is a great opportunity for someone who wants to work at the intersection of consulting, public policy and social impact—and who is excited by the challenge of using data and evidence to help governments solve complex problems.

Key responsibilities

  • Work with clients to understand their challenges, define problems, identify goals and create evaluation frameworks and work plans
  • Support primary data collection and analysis (e.g., programming and fielding surveys, cleaning and analyzing survey data, supporting interviews or focus groups, conducting thematic analysis of qualitative data, etc.)
  • Facilitate client and stakeholder workshops, focus groups and interviews
  • Contribute to project coordination and logistics including organizing meetings, taking minutes, updating workplans and tracking budgets
  • Work collaboratively to interpret findings from multiple lines of inquiry and translate them into actionable insights, options and recommendations for our clients
  • Draft high-quality client deliverables including briefing notes, presentation decks, reports, and knowledge mobilization materials
  • Contribute to secondary research including literature reviews and jurisdictional scans
  • Contribute to business development activities including project proposals and pitches

The successful candidate will demonstrate Blueprint’s values of being evidence-driven, people-centred, curious, accountable, and optimistic . They will contribute to communities of practice and professional networks both within and outside of Blueprint.

What we’re looking for
Minimum requirements

  • Master’s degree in the Social Sciences (e.g., Economics, Urban Planning, Psychology, Public Health, Political Science), Public Policy, Global Affairs or Public Administration
  • 2-5 years experience working in a public sector consulting and/or evaluation and research
Knowledge and skills
  • Experience with a range of applied research techniques and evaluation methodologies
  • Policy domain knowledge in at least one of the following areas: employment, income security, mental health, child and youth development, housing, community safety, and justice
  • Excellent oral and written communication skills, with a demonstrated ability to synthesize complex information into clear and concise client-facing materials
  • High standards for accuracy, attention to detail and professional judgement
  • A collaborative team player who brings curiosity, humility and an ability to work in a fast-paced, dynamic and agile work environment
  • Strong time management and organizational skills; able to navigate tight timelines, actively communicate progress, proactively problem-solve
  • Eagerness to contribute to a high-performance, feedback-oriented team culture
  • Proficiency with Microsoft software (Word, PowerPoint, Excel) and willingness to learn and use other tools and platforms (e.g., Qualtrics, Miro, Condens)

What we offer
To ensure team members are supported to do their best work, Blueprint provides:
  • A mission-driven culture focused on public good and values learning and impact
  • Growth opportunities and mentorship in a supportive environment
  • Comprehensive medical, dental, and vision benefits, plus life and disability insurance and mental health supports through GreenShield+.
  • RRSP matching of up to 6%.
  • Monthly cell-phone allowance and a one-time stipend to support home-office set-up.
  • Up to 18 days vacation annually, plus six universal leave days and year-end office closure (December 25 and January 1)
  • Annual stipends for professional development, conferences, memberships and certifications.
How to apply
We take care in ensuring that new team members align with our mission and are positioned for success in their roles. Please apply by September 12, 2025.  Selected candidates will be invited to:
  1. Complete a short assignment that reflects the type of work an Associate would do
  2. Submit two writing samples
  3. Participate in an in-person interview at Blueprint’s Toronto office
Commitment to equity, diversity, and inclusion
Blueprint is strongly committed to equal opportunities in employment and reflecting the diverse communities we serve. We recognize that diversity enriches our approach to problem solving and contributes to an inclusive work environment. Thus, we welcome and encourage applications from people of all identities and lived experiences, including women, Indigenous Peoples, persons with disabilities, and members of the 2SLGBTQIA+ community. If your background or lived experience equips you for this role but doesn't exactly match the listed qualifications, please highlight this in your responses to the application questions.

Accommodations
Blueprint is committed to creating an accessible and inclusive workplace. We are committed to providing barrier-free and accessible employment practices in compliance with the Accessibility for Ontarians with Disabilities Act (AODA). Accommodations are available on request for candidates taking part in the selection process. Please contact to ensure that we can best meet your needs.
 

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Research Associate, Preclinical

Vancouver, British Columbia Acuitas

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Salary: $80,000-$100,000

Acuitas Therapeutics is a private biotechnology company based in Vancouver, British Columbia, Canada. We are the premier global provider of LNP delivery systems for nucleic acid therapeutics. Acuitas is partnered with multiple international, biotechnology and pharmaceutical partners who are focused on bringing new vaccines and drugs into clinical development and to the marketplace.


At Acuitas, we believe in combining excellent science with an enviable work culture. The advanced LNP technologies we provide for our partners are made possible by our employees who apply their passion, curiosity, and knowledge every step of the way. At Acuitas, you will have the opportunity to work as part of a close-knit team of exceptional scientists, who support the production of revolutionary technology that impacts the health and wellness of society. By living our values, including honesty, integrity, innovation and openness, we have fostered a supportive work environment where our employees feel empowered, challenged, recognized and rewarded. If you would like to work for a company that is at the top of the field, Acuitas is the company for you!


All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or any other status protected by applicable law.



Job Title: Research Associate, Preclinical


YOU: A committed professional with experience in preclinical research looking to develop further in an innovative, fast paced biotech environment.

US: Leading innovators in the lipid nanoparticle (LNP) field, looking for a talented individual to join our collaborative, passionate, and diverse results focused team.

ROLE SUMMARY: Acuitas Therapeutics is seeking a Research Associate with a strong background in immunology and immunological methods to work in the Preclinical team, reporting to the Senior Research Scientist, Preclinical. The role holder will be responsible for executing and supporting studies assessing the pharmacology, immunology, mechanism of action, distribution and safety profile of our LNP, executing analyses and data interpretation, and presenting results to the team and company.

Working with the Preclinical team, the responsibilities would include:

  1. Executing and supporting studies to evaluate LNP activity, distribution, mechanisms of action, immune profiles and safety.
  2. Mastering established methods and developing new methods to support preclinical objectives, including ELISA, MSD, luciferase assays, qPCR, SDS-PAGE, DNA/RNA isolation and protein quantification.
  3. Cell culture and cell-based assays (including ELIspot), cell isolation, and processing tissues and fluids for downstream analysis.
  4. Hands-on experience in multi-colour flow cytometry, intracellular cytokine staining and gating strategies.
  5. General laboratory support including preparation of reagents and solutions, laboratory organization, maintaining sample and reagent inventory, and shipping of materials.
  6. Up to date Biosafety/Biosecurity (Containment Level 2+) and WHMIS certification will be required.
  7. Maintain familiarity with relevant scientific knowledge and advancements in LNP technology.
  8. May be required to train more junior staff and co-op students.



QUALIFICATIONS AND SKILLS:

  • BSc with 2-10 years experience or an MSc with up to 7 years experience; some industry experience preferred.
  • Hands-on experience conducting experiments with LNP in vitro and ex vivo; knowledge of LNP formulation processes, LNP characteristics, in vivo biodistribution, pharmacodynamics and pharmacokinetics
  • Strong background in innate and adaptive immunology. Knowledge specific to LNP preferred.
  • Strong understanding of cell biology and human physiology with a focus on liver structure and function as well as other fenestrated organs.
  • Background in vaccine development and experience conducting/analyzing associated assays (ELISA, EliSpot, HAI)
  • Hands-on experience in tissue isolation, single cell preparation, cell culture, cell-based assays and cell differentiation.
  • Extensive experience in multiplex immune-based assays. Specifically Meso Scale Diagnostics and multichannel flow cytometry including the development of gating strategies.
  • Confident and proven safety when working in Biosafety Level 2+ environments.
  • Excellent writing and presentation skills. Accurate and appropriate data analysis and use of statistics.
  • Familiar with Spotfire and Big Omics or similar visualization platforms. Fluent working with Graph Pad and Microsoft Office. Adept utilizing Flo Jo or similar.
  • Responsible and reliable record keeping, organization and assisting in lab management as needed.


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Lead Clinical Research Associate

Toronto, Ontario PSI CRO

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PSI is a leading Contract Research Organization with more 30 years in the industry, offering a perfect balance between stability and innovation to both clients and employees.  We focus on delivering quality and on-time services across a variety of therapeutic indications.

Job Description

  • Coordinates investigator/ site feasibility and identification process, as well as study startup.
  • Monitors project timelines and patient enrollment, implements respective corrective and preventive measures.
  • Reviews monitoring visit reports for all visit types and ensures reporting compliance of the Monitors in the region.
  • Manages Monitors in the query resolution process, including Central Monitoring observations.
  • Coordinates safety information flow and protocol/process deviation reporting.
  • Performs clinical supplies management with vendors on a country and regional level.
  • Ensures study-specific and corporate tracking systems are updated in a timely manner.
  • Acts as the main communication line between Monitor, Site Management Associate, Regional Project Lead, and/ Project Manager.
  • Coordinates planning of supervised monitoring visits and conducts the visits. 
  • Manages the project team in site contracting and payments.
  • Leads project team calls on a country level as well as provides status updates and reports to Regional Lead/ Project Manager.
  • Ensures ongoing evaluation of data integrity and compliance at a country/regional level.
  • Conducts site audit preparation visits, may participate in site audits, and coordinates resolution of site audit findings on a country/regional level.
  • Oversees project team in CAPA development and implementation.
  • Coordinates project team in process deviations review, management and reporting.
  • Conducts initial training and authorization monitoring visits for Monitors and acts as a mentor for newly promoted Lead CRAs.
  • Provides project-specific training and prepares training materials for the project team under supervision of a Project Manager and Regional Project Lead.
  • Delivers trainings and presentations at Investigator Meetings.
  • Prepares, conducts and reports site selection, initiation, routine monitoring and closeout visits.
  • Ensures that subject recruitment targets and project timelines are properly defined, communicated, recorded, and met at site level.
  • Ensures accurate and timely information flow with trial sites on Adverse Events and protocol/process deviations.
  • Supervises source data verification and follows up on data queries at site level in the country/region; reviews and manages study risks on a site level.
  • Ensures proper handling, use, accountability, reconciliation, and return of all Investigational Product(s) and clinical study supplies on a country/region level.
  • Reviews essential study documents and supervises reconciliation of study Investigator Site File (ISF) / TMF at site level and country/region level.
  • Ensures data integrity and compliance at a site level.
  • Supervises Site Management Associates in the flow of documents and laboratory supplies between the site and the Central/ Regional Lab/ Central Reviewer.
  • Conducts project-specific training of site Investigators.
  • Supports preparation of draft regulatory and ethics committee submission packages.
Qualifications

  • Relevant educational background, such as MD, MPharm, RN or College/University degree in Life Sciences or an equivalent combination of education, training and experience.
  • Minimum of 5 years’ site monitoring experience with participation in global clinical projects as a Lead Monitor. 
  • Must have prior experience monitoring or managing sites and CRAs in the United States with knowledge of US regulatory guidelines and practices. 
  • Experience with all types of monitoring visits in Phases I-III. 
  • Strong experience in Oncology preferred.
  • Experience in CAR-T Therapy or other types of Cell Therapy, Gene Therapy, Radiation Therapy or Radiopharmaceuticals, or Nuclear Medicine is preferred. 
  • Strong experience in GI (Chron's, Ulcerative Colitis, IBS) preferred. 
  • Full working proficiency in English.
  • Proficiency in MS Office applications.
  • Ability to plan, multitask and work in a dynamic team environment.
  • Excellent Communication, collaboration, and problem-solving skills.
  • Ability to travel up to 65% (depending on project needs).
  • Valid driver’s license (if applicable).


Additional Information

All your information will be kept confidential according to EEO guidelines.

For this position, PSI is not hiring individuals who require work visa for employment or continued employment now or anytime in the future.

This advertiser has chosen not to accept applicants from your region.
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